Copied from Wikipedia "List of unsolved Problems in Physics":Link

Interpretation of quantum mechanics: How does the quantum description of reality, which includes elements such as the superposition of states and wavefunction collapse or quantum decoherence, give rise to the reality we perceive?^{[4]} Another way of stating this question regards the measurement problem: What constitutes a "measurement" which apparently causes the wave function to collapse into a
definite state? Unlike classical physical processes, some quantum mechanical processes (such as quantum teleportation arising from quantum entanglement) cannot be simultaneously "local", "causal", and "real", but it is not obvious which of these
properties must be sacrificed,^{[5]} or if an attempt to describe quantum mechanical processes in these senses
is a category error such that a proper understanding of quantum mechanics would render the question meaningless. Can a
multiverse resolve it?

Yang–Mills theory: Given an arbitrary compact gauge group, does a nontrivial quantum Yang–Mills theory with a finite mass gap exist? (This problem is also listed as one of the Millennium Prize Problems in mathematics.)^{[6]}

Color confinement: Quantum chromodynamics (QCD) color confinement conjecture is that color charged particles (such as
quarks and gluons) cannot be separated from their parent hadron without producing new hadrons.^{[7]} There is not yet an analytic proof of color confinement in any nonabelian
gauge theory.

Physical information: Are there physical phenomena, such as wave function collapse or black holes, that irrevocably destroy information about their prior states?^{[8]} How is quantum information stored as a state of a quantum system?

Dimensionless physical constant: At the present time, the values of the dimensionless physical constants
cannot be calculated; they are determined only by physical measurement.^{[9]}^{[10]} What is the minimum number of dimensionless physical constants
from which all other dimensionless physical constants can be derived? Are dimensional physical constants necessary at all?

Quantum field theory: Is it possible to construct, in the mathematically rigorous framework of algebraic QFT, a theory in 4dimensional spacetime that includes interactions and does not resort to
perturbative methods?^{[14]}^{[15]}
All interpretations of quantum mechanics are biased interpretations. New Physics replaces all theories of quantum mechanics by scientific principles of
classical physics. (Link New Physics)
All questions concerning issues of quantum mechanics are eliminated because quantum theories are no reality. Examples:
YoungMills theory/ compact gauge Group
no reality
Color confinement
no reality
Wave function collapse
no reality
Quantum field theory
no reality
Physical information
All interactions of particles have to meet principle of energy conservation and thus properties after interactions are fully defined by properties before
interactions. There are no physical phenomena, which violate this principle. There are no interactions where physical information gets lost.
Dimensionless physical constants (concerning quantum theories)
do not describe anything which is physical (=reality) and thus are not needed and can be eliminated.